Angioedema is frequently categorized into:
- histamine-mediated disease
- bradykinin-mediated disease
It is critical to determine the underlying mediator of symptoms as it directs treatment.
Histaminergic angioedema is the most frequent cause of angioedema. It is classified as:
- acute (lasting less than 6 weeks)
- chronic (symptoms for longer than 6 weeks)
It is further classified into angioedema presenting with or without urticaria.
Mast cells and basophils are central to the underlying pathophysiology of histamine-mediated angioedema.
The underlying treatments of histamine-mediated angioedema are:
Histaminergic Angioedema http://buff.ly/2ryJ5dn